The patron of Orsogna is Saint Nicholas of Bari, celebrated on 6 December in the Church of San Nicola.
The town is renowned for the Festa dei Talami, an ancient tradition of living biblical tableaux renewed every year on the morning of the Tuesday after Easter and the evening of Ferragosto (15 August), which has grown considerably since the 1990s. Although the church of the Black Madonna was destroyed in the bombings of 1943-44, its feast is still celebrated today between the Monday and Tuesday after Easter. The town also holds the Convento del Ritiro della Santissima Annunziata del Poggio.
