The patron of San Gregorio d'Ippona is Saint Gregory the Great, celebrated on 12 March in the Church of San Gregorio Magno.
The town holds the Shrine of Maria Santissima della Salute, the Church of Santa Maria Maggiore, the Church of Maria Santissima delle Grazie and the Church of Maria Santissima del Buon Consiglio, as well as the Villa Comunale.