The patron of Osoppo is Saint Columba, celebrated on 7 July.
From the 1990s until 2010, the town hosted in early July, at the Parco del Rivellino, the Rototom Sunsplash, one of the most important reggae music festivals in Europe. The town holds the Fortress of Osoppo and a rare paleo-Christian church, as well as the Church of Santa Maria ad Nives.