The patron saints of San Mauro Marchesato are Maria Santissima del Soccorso (Most Holy Mary of Help), patroness of the town, and San Giovanni Battista (Saint John the Baptist), patron of the parish, celebrated on the first Sunday of June; the village holds the Santuario Madonna del Soccorso.
The municipality also holds the Chiesa dell'Immacolata and the Chiesa di San Giovanni Battista.