The patron of Melicucco is Bishop Saint Nicholas, celebrated on 6 December in the mother church named after him, the Church of San Nicola Vescovo.
On 16 August, instead, the feast of Saint Roch is celebrated, preceded by the «ciuccio», a papier-mâché donkey rigged with pyrotechnic gunpowder. The town also holds the «I Due Pini» park.