The patron of Buttrio is Our Lady of the Assumption, celebrated on 15 August in the Church of Santa Maria Assunta.
The town is known for the Fiera Regionale dei Vini di Buttrio, one of Italy's oldest wine events: in 2023 it reached its ninetieth edition. The town also holds the Castello di Buttrio and the Museum of Wine Civilization, as well as the small Church of Santi Gervasio e Protasio.