The patron of Lioni is Saint Roch, celebrated on 16 August in the Church of San Rocco.
On 17 August, «la serata del cantante» is held, an evening of music celebrating the local Ferragosto. On 8 December, instead, the so-called «Madonna de lo fuoco» is celebrated, with immense bonfires lit. The town also holds the Shrine of Santa Maria del Piano and the Teatro comunale di Lioni.