The patron saint of San Colombano al Lambro is Saint Columban, celebrated on 21 November.
For nearly two centuries, on 16 August, the feast of Saint Roch, the Oratory has opened to the public in the morning for the celebration of Mass and in the evening for a solemn blessing with the exposition of the saint's relic. The town also holds the Castello Belgioioso and the Virginio Caccia Palaeontological and Archaeological Museum.