The patron saint of Potenza Picena is Saint Girio, celebrated on 25 May in the Sanctuary of San Girio.
At Christmas, about two hundred characters bring to life the Living Nativity in the woods of the Convent of the Friars Minor, over an area of two thousand square metres. On the occasion of the Festa del Grappolo d'Oro, the town also hosts delegations from its twin towns of Templemore, Burford and Premilhat. The municipal territory also holds Villa Buonaccorsi and the Church of San Francesco.
