Among the patrons of Supino is Saint Cataldus, celebrated on 10 May.
The town's other patron, Saint Lawrence, is celebrated on 10 August. Since the early Middle Ages, Saint Anthony the Abbot has also been celebrated, with two feasts: one on 16 and 17 January, with the distribution of blessed bread rolls and the blessing of animals, and the other on the last Sunday of September, with a procession and civic celebrations. The town also holds the Roman Villa of Supino.