The patron of Gropello Cairoli is Saint George the Martyr, whose equestrian statue fighting the dragon overlooks the Church of San Giorgio Martire, the town's mother church; the feast is celebrated on the Sunday nearest to 23 April.
For over 70 years, in early September, the Festa dei Ragazzi has been held, one of the town's most established traditions: children and teenagers representing the town's four districts, Castello, Parrocchia, Stazione and San Rocco, compete against each other. The town also holds the Chapel of the Madonna del Rosario.