The patroness of Campotosto is Maria Santissima della Visitazione (the Blessed Virgin of the Visitation), celebrated on 2 July.
The village produces the typical mortadella di Campotosto, a Slow Food presidium and a traditional agri-food product of Abruzzo. The municipality also holds the parish church of Santa Maria Assunta, the Chiesa di San Giorgio, Santa Maria Apparente and the Madonna di Pedicino.