The patron of Murlo is Saint Fortunatus, celebrated on 12 July in the Church of San Fortunato.
The area holds Poggio Civitate, one of the most important Etruscan archaeological sites in Tuscany. The town also holds the Cappella di Santa Maria a Piantasala, the Pieve dei Santi Giusto e Clemente and the Church of Santi Pietro e Paolo.
