The patron saint of Isola della Scala is Saint James the Greater, celebrated with the patronal feast of San Giacomo e Sant'Anna at the end of July.
Since 1967, the Rice Fair has been held, the largest Italian food and wine fair dedicated to rice, the biggest event in Italy and second in Europe by attendance after Munich's Oktoberfest, between mid-September and mid-October. The town also holds the Church of Santo Stefano Protomartire and the Torre Scaligera.