The patron of Casaletto Spartano is Saint Nicholas of Bari, celebrated on 13 May, to whom the Chiesa di San Nicola is dedicated; 15 August and 8 September are also listed among the municipality's feast days.
The municipality also holds the Santuario Madonna di Martiri, the Chiesa di San Giuseppe and Palazzo Gallotti, as well as Monte Rotondo and the Cilento, Vallo di Diano and Alburni National Park.