The patron of Clusone is Our Lady of the Assumption, celebrated on 15 August in the Basilica di Santa Maria Assunta e San Giovanni Battista; the co-patron, Saint John the Baptist, is instead celebrated on 24 June.
Since 1952 the local tourist association has organised the traditional Clusone Carnival, with a parade of floats. The town also holds the small Church of San Lucio and Palazzo Fogaccia.