The patron saint of Montespertoli is Saint Andrew the Apostle, celebrated on 30 November.
In March, in the hamlet of Anselmo, the traditional Sagra del Bombolone is held. From the last Saturday of May to the first Sunday of June, the Wine Festival takes place, formerly the Chianti Exhibition, organized by the town council to promote the main product of local agriculture. The town holds the Church of San Bartolomeo and the Church of San Pietro.