The patron of Lozzolo is Saint George, celebrated on 23 April, after whom the parish church of San Giorgio is named.
The municipality in the province of Vercelli holds the Castello di Lozzolo, the Santuario della Madonna Annunziata and the oratories of San Sebastiano and of Saints Roch and Anthony Abbot, while the Riserva naturale delle Baragge is among the sites of its territory.