One of the patrons of Sammichele di Bari is Saint Vitus the martyr: the feast was traditionally celebrated on 9 May, but since 2009, by archiepiscopal decree, it has been moved to the Monday after the second Sunday of May.
The other patron, Saint Michael the Archangel, is celebrated the preceding Sunday. The town also holds the shrine of San Francesco d'Assisi and the Grave di Frassineto.