The patron saint of Macomer is Saint Pantaleon, celebrated on 27 July in the Church of San Pantaleo.
Of considerable historical and natural importance is the Mount of Saint Anthony, where on 13 June the celebrations for the saint of Padua are held, drawing thousands of faithful and tourists. The town also holds the Tamuli and the Nuraghe Cabudbbene, as well as the Nuraghe Trina.