The patron of Ameno is the Assumption of Mary (Assunzione di Maria), celebrated on 15 August; the municipality holds the Chiesa di Santa Maria Assunta.
A religious feast is celebrated every year on the first Sunday of September and always draws a large number of people; in June an important blues festival called «Amenoblues» takes place. The municipality also holds the Santuario della Madonna della Bocciola, the Museo Fondazione Calderara and the Museo Tornielli.