The patron saint of Regalbuto is Saint Vitus the martyr, celebrated on 11 August: the patronal feast in his honour is deeply felt and lasts five days, from 7 to 11 August, with the traditional laurel procession held on 8 August.
The town preserves numerous historic churches, including those of San Basilio, Santa Maria la Croce, San Sebastiano and the Immaculate Conception, as well as the Hermitage of Sant'Antonio Abate. Near Regalbuto lies Lake Sciaguana, an important artificial reservoir in the Enna area.