The patron saints of Varallo Pombia are Saints Vincent and Anastasius, celebrated on the first Tuesday after Easter in the Church of Santi Vincenzo e Anastasio.
Co-patroness is Saint Anne, celebrated on 26 July with a procession through the town's streets carrying her statue. On the first Saturday of September, a votive pilgrimage to the Sacro Monte di Varese is also held. The municipal territory also holds the Sanctuary of the Madonna del Rosario and the church of the Santissima Trinità.