The patron saint of Sinagra is Saint Leo of Catania, celebrated on 8 May; the town holds a church dedicated to him.
A papal bull records the assignment of the Sinagra settlement to the church of Messina. According to tradition, in 1053 Count Roger, a guest of the monastery of San Nicolò di Raccuja, one of the most important Basilian monasteries of the Nebrodi, went round the fiefs of Sinagra, Naso and Ficarra and is said to have granted them to the numerous monastic orders active in the territory. The medieval castle was enlarged and churches and convents were built; by 1460 the barony was so powerful that it obtained from King John criminal jurisdiction over the entire fief. From the 16th century the barony of Sinagra was ruled by the Afflitto family, who, more tied to their southern fief, later ceded the territory to the Ventimiglia family. Among the town's other religious buildings are the mother church of San Michele Arcangelo and the church of the Crocifisso.