The patron saint of San Salvatore di Fitalia is Saint Calogerus the Hermit, venerated in the sanctuary dedicated to him and celebrated on 20 August. His cult is documented locally at least since 1537, and over time became one of the main elements of Fitalese religious identity. In 1615 a convent of Franciscan Minor Conventual friars was established, with an attached chapel dedicated to the saint: the chapel and convent were lost in a landslide around the mid-19th century, and in the early 20th century, on the area they once occupied, a hospital was built, named precisely after the patron saint.
The town also preserves the church of the Holy Saviour, the main religious building of the centre, whose origins date back to the Byzantine era; it was later rebuilt and transformed during the Norman period, when the nearby, older settlement of Fitalia progressively lost importance to the nucleus that developed around the castle and the church of the Saviour. During the Norman period the territory was divided between the jurisdiction of the bishop of Patti and that of the archbishop of Messina together with the Benedictine monastery of the Holy Saviour of San Marco d'Alunzio.