The patron saint of Mioglia is Saint Andrew the Apostle, celebrated on 30 November. The church dedicated to him, in the main village, was built between 1650 and 1750 in Baroque style: it features an old stone portal from 1701 and a carved wooden altar.
The town reached its greatest historical standing under the Scarampi family of Asti, who owned the land from 1469 and in 1536 requested the establishment of an autonomous imperial fief under the Spanish governor of Milan, as imperial vicar of the fiefs of the Langhe. The relationship between the people of Mioglia and their Asti feudal lords was marked throughout the 16th and 17th centuries by periods of pacification alternating with outright rebellions by the town's main families against the power and alleged abuses of the Scarampi, compounded by border clashes with the communities of Pareto and Sassello, attacks on the local castle during the War of Monferrato in 1638, and a Savoyard reprisal in 1664; in 1738 Mioglia was finally annexed to the Kingdom of Sardinia. The castle of Mioglia, built in the 13th century in a strategic position along the road to the Alessandria town of Pareto, was razed to the ground by the Spanish army in the 17th century, leaving today only a few wall remains; in the town centre stands instead Palazzo Scarampi, built in 1687 by the feudal family and still adorned today by their coat of arms above the portal.
